Valoración de la proteinuria en la enfermedad renal: evaluación metodológica

Abstract

Chronic kidney disease is a public health problem that requires global action strategies for both early detection and for monitoring. Proteinuria is considered a marker of renal injury. In this sense, the present work evaluates the clinical laboratory from the most relevant methodological aspects for assessment. These considerations preanalytical stage as patient conditions include; sample type and form of conservation. Methods and quantitative screening for proteinuria and albuminuria are described. The usefulness of immunological analysis of specific marker proteins stands for characterizing the quality of the protein deleted. Given the implication of measuring urinary protein loss, the laboratory should focus on the clinical need for accurate and clearly reported values.